DocumentCode
761529
Title
Focusing fluids and light
Author
Mao, Xiaole ; Huang, Tony Jun
Author_Institution
Dept. of Bioeng., Penn State Univ., University Park, PA
Volume
2
Issue
1
fYear
2008
fDate
3/1/2008 12:00:00 AM
Firstpage
22
Lastpage
27
Abstract
There exist two major technical challenges when developing on-chip single- particle detection systems: focusing the particles and focusing the light. Flow cytometry is used to measure the optical and fluorescence characteristics of single cells while cells pass through an optical interrogation area (with dimensions on the order of several micrometers to tens of micrometers) that is defined by a focused laser beam.
Keywords
bioMEMS; cellular biophysics; laser applications in medicine; flow cytometry; focused laser beam; light focusing; on-chip single-particle detection systems; optical interrogation; particles focusing; single cells; Biomedical optical imaging; Coaxial components; Fluorescence; Hydrodynamics; Laser excitation; Microfluidics; Optical devices; Optical sensors; Optical waveguides; System-on-a-chip;
fLanguage
English
Journal_Title
Nanotechnology Magazine, IEEE
Publisher
ieee
ISSN
1932-4510
Type
jour
DOI
10.1109/MNANO.2008.920048
Filename
4547905
Link To Document