Title :
Biotechnology-based recognition elements
Author :
Schultz, Jerome S.
Author_Institution :
Center for Biotechnol. & Bioeng., Pittsburgh Univ. Sch. of Med., PA, USA
Abstract :
The author discusses technology, applications, and opportunities for biosensors. The following topics are considered: the shape of the myoglobin molecule; a schematic structure of an antibody showing the different regions of the molecule; the form of the membrane-bound acetylcholine receptor protein; forces responsible for interactive behavior between receptors and ligands; a photolithographic technique for the production of a peptide library on a chip; the principle of affine chromatography; the structure of a glucose electrode developed by Leland Clark; interferences with an enzyme-based glucose biosensor; components of biosensors; a glucose sensor based on fiber optics.<>
Keywords :
biosensors; biotechnology; chromatography; fibre optic sensors; photolithography; proteins; reviews; Leland Clark; affine chromatography principle; antibody schematic structure; biosensors components; biotechnology-based recognition elements; enzyme-based glucose biosensor interferences; fiber optic-based glucose sensor; glucose electrode structure; interactive behavior forces; membrane-bound acetylcholine receptor protein; myoglobin molecule shape; peptide library on chip production; photolithographic technique; receptors/ligands interactions; Biosensors; Electrodes; Interference; Libraries; Optical fiber sensors; Peptides; Production; Protein engineering;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
