Title :
Electrofusion processes: theoretical evaluation of high electric field effects on cellular transmembrane potentials
Author :
Gaynor, P.T. ; Bodger, P.S.
Author_Institution :
Dept. of Electr. & Electron. Eng., Canterbury Univ., Christchurch, New Zealand
fDate :
3/1/1995 12:00:00 AM
Abstract :
A theoretical evaluation of cellular transmembrane potential is used to investigate the effect of dynamic high magnitude electric fields specific to the electrofusion process. A numerical computer model is designed for the purpose. Conventional DC impulse techniques for electrofusion are found to be less efficient than AC electric fields in both an electrical and a biological sense
Keywords :
bioelectric potentials; biology computing; biomembrane transport; cellular biophysics; digital simulation; electric field effects; electrophoresis; physiological models; AC electric fields; DC impulse techniques; biological processes; cellular transmembrane potential; dynamic high magnitude electric fields; electrofusion; high electric field effects; numerical computer model;
Journal_Title :
Science, Measurement and Technology, IEE Proceedings -
DOI :
10.1049/ip-smt:19951454
