Title :
Effects of Magnetic Field and Magnetoliposomes on Mice: Cytotoxicity and Genotoxicity Tests
Author :
Barbosa, Luzirlane S. ; Sadeghiani, Neda ; Guedes, Maria H A ; Oliveira, Daniela M. ; Tedesco, Antonio C. ; Lima, Emília C O ; Azevedo, Ricardo B. ; Morais, Paulo C. ; Lacava, Zulmira G M
Author_Institution :
Inst. de Ciencias Biologicas, Univ. de Brasilia
Abstract :
In the present work, some biological effects of the AC magnetic field exposure after magnetoliposome sample treatment were investigated through micronucleus assay and blood and peritoneum cytometry. Data showed that after 5 min exposure AC magnetic field might induce inflammatory reactions, genotoxicity, and cytotoxicity. We conclude that under our experimental conditions magnetohyperthermia experiments may be safely conducted by 3-min AC magnetic field exposure
Keywords :
biological effects of fields; cellular effects of radiation; hyperthermia; toxicology; 3 min; 5 min; alternating magnetic field; biological effects; cytometry; cytotoxicity tests; genotoxicity tests; magnetohyperthermia; magnetoliposome; magnetoliposomes; micronucleus; Blood; Bones; Cells (biology); Cobalt; Frequency; Hyperthermia; Magnetic fields; Mice; Nanoparticles; Testing; Alternating magnetic field; cytometry; hyperthermia; inflammation; magnetoliposome; micronucleus;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2006.879962
