• DocumentCode
    770475
  • Title

    In silico environments augment clinical trials

  • Author

    Sieburg, Hans B.

  • Author_Institution
    Lab. for Biological Informatics & Theoretical Medicine, California Univ., San Diego, La Jolla, CA, USA
  • Volume
    15
  • Issue
    2
  • fYear
    1996
  • Firstpage
    47
  • Lastpage
    59
  • Abstract
    One of the most promising new approaches to interpreting complex systems data is to generate self-organizing simulations. We have previously applied Markov random field methods to create virtual worlds for the prototyping of wetlab experimentation. We have termed the virtual worlds “in silico environments” to express a synergism between computer simulation and wetlab experimentation. We show that in silico environments allow the planning of clinical trial procedures. A strong aspect of the method is the use of a dedicated object oriented language called Slang (simulation language)
  • Keywords
    Markov processes; digital simulation; medical computing; object-oriented languages; simulation languages; virtual reality; Markov random field methods; Slang; clinical trials; complex systems data; computer simulation; distributed in silico environments; object oriented language; planning; prototyping; self-organizing simulation; simulation language; virtual reality; wetlab experimentation; Biological system modeling; Bridges; Clinical trials; Instruments; Internet; Markov random fields; Medical simulation; Packaging; TCPIP; World Wide Web;
  • fLanguage
    English
  • Journal_Title
    Engineering in Medicine and Biology Magazine, IEEE
  • Publisher
    ieee
  • ISSN
    0739-5175
  • Type

    jour

  • DOI
    10.1109/51.486719
  • Filename
    486719