A Novel Interface for Hybrid Mock Circulations to Evaluate Ventricular Assist Devices

Author

Ochsner, Gregor ; Amacher, Raffael ; Amstutz, A. ; Plass, A. ; Schmid Daners, Marianne ; Tevaearai, H. ; Vandenberghe, Stefaan ; Wilhelm, M.J. ; Guzzella, Lino

Author_Institution

Inst. for Dynamic Syst. & Control, ETH Zurich, Zurich, Switzerland

Volume

60

Issue

2

fYear

2013

fDate

Feb. 2013

Firstpage

507

Lastpage

516

Abstract

This paper presents a novel mock circulation for the evaluation of ventricular assist devices (VADs), which is based on a hardware-in-the-loop concept. A numerical model of the human blood circulation runs in real time and computes instantaneous pressure, volume, and flow rate values. The VAD to be tested is connected to a numerical-hydraulic interface, which allows the interaction between the VAD and the numerical model of the circulation. The numerical-hydraulic interface consists of two pressure-controlled reservoirs, which apply the computed pressure values from the model to the VAD, and a flow probe to feed the resulting VAD flow rate back to the model. Experimental results are provided to show the proper interaction between a numerical model of the circulation and a mixed-flow blood pump.

Keywords

biomedical equipment; blood; cardiology; flow simulation; haemodynamics; medical computing; numerical analysis; prosthetics; flow rate values; hardware-in-the-loop concept; human blood circulation; hybrid mock circulation interface; instantaneous pressure values; mixed-flow blood pump; numerical model; numerical-hydraulic interface; pressure-controlled reservoirs; ventricular assist devices; volume values; Blood; Computational modeling; Fluids; Numerical models; Physiology; Pumps; Valves; Feedback control; hardware-in-the-loop; mechanical circulatory support (MCS); mock circulation; ventricular assist device (VAD); Computer Simulation; Equipment Design; Feedback; Heart-Assist Devices; Humans; Models, Cardiovascular; Pressure; Signal Processing, Computer-Assisted;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/TBME.2012.2230000

Filename

6362188