Title :
From Einthoven´s galvanometer to single-channel recording
Author :
Schoenfeld, Robert L.
Author_Institution :
Rockefeller Univ., New York, NY, USA
Abstract :
This article discusses the innovations which made it possible to do single-channel recording and to study the release of chemical ions from a single channel in the cell membrane. Topics covered include: Herbert Gasser´s use of electronics; Detlev Wulf Bronk as scientist and supporter of science; Hodgkin and Huxley probing inside the nerve; synaptic chemical transmission and quantum release; and inhibition and excitation in the horseshoe crab eye
Keywords :
biological techniques; biomembrane transport; eye; history; neurophysiology; Detlev Wulf Bronk; Einthoven galvanometer; Herbert Gasser; Hodgkin; Huxley; cell membrane; chemical ion release; electronics; excitation; historical innovations; horseshoe crab eye; inhibition; nerve; quantum release; single-channel recording; synaptic chemical transmission; Animal structures; Bandwidth; Cathode ray tubes; Central nervous system; Chemicals; Magnetic field measurement; Nerve fibers; Permission; Physiology; Software libraries;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2002.1016853
