Title :
Confocal microwave imaging for breast cancer detection: localization of tumors in three dimensions
Author :
Fear, Elise C. ; Li, Xu ; Hagness, Susan C. ; Stuchly, Maria A.
Author_Institution :
Dept. of Electr. & Comput. Eng., Calgary Univ., Alta., Canada
Abstract :
The physical basis for breast tumor detection with microwave imaging is the contrast in dielectric properties of normal and malignant breast tissues. Confocal microwave imaging involves illuminating the breast with an ultra-wideband pulse from a number of antenna locations, then synthetically focusing reflections from the breast. The detection of malignant tumors is achieved by the coherent addition of returns from these strongly scattering objects. In this paper, we demonstrate the feasibility of detecting and localizing small (<1 cm) tumors in three dimensions with numerical models of two system configurations involving synthetic cylindrical and planar antenna arrays. Image formation algorithms are developed to enhance tumor responses and reduce early- and late-time clutter. The early-time clutter consists of the incident pulse and reflections from the skin, while the late-time clutter is primarily due to the heterogeneity of breast tissue. Successful detection of 6-mm-diameter spherical tumors is achieved with both planar and cylindrical systems, and similar performance measures are obtained. The influences of the synthetic array size and position relative to the tumor are also explored.
Keywords :
backscatter; cancer; clutter; image reconstruction; mammography; medical image processing; microwave imaging; motion compensation; tumours; array position; backscatter; breast tumor detection; coherent addition of returns; confocal microwave imaging; dielectric properties contrast; early-time clutter; image formation algorithms; image reconstruction; late-time clutter; malignant breast tissues; normal breast tissues; numerical models; object detection; single-signal analysis; spherical tumors; strongly scattering objects; synthetic array size; synthetic cylindrical antenna arrays; synthetic planar antenna arrays; three dimensional localization; three-dimensional volumetric map; tissue heterogeneity; ultra-wideband pulse; Breast cancer; Breast neoplasms; Breast tissue; Breast tumors; Cancer detection; Dielectrics; Microwave antennas; Microwave imaging; Reflection; Ultra wideband technology; Algorithms; Breast Neoplasms; Calibration; Computer Simulation; Electromagnetics; Equipment Design; Humans; Imaging, Three-Dimensional; Microscopy, Confocal; Microwaves; Models, Anatomic; Phantoms, Imaging; Sensitivity and Specificity;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2002.800759