• DocumentCode
    796874
  • Title

    Incomplete Lineage Sorting: Consistent Phylogeny Estimation from Multiple Loci

  • Author

    Mossel, Elchanan ; Roch, Sebastien

  • Author_Institution
    Dept. of Stat., Univ. of California, Berkeley, CA, USA
  • Volume
    7
  • Issue
    1
  • fYear
    2010
  • Firstpage
    166
  • Lastpage
    171
  • Abstract
    We introduce a simple computationally efficient algorithm for reconstructing phylogenies from multiple gene trees in the presence of incomplete lineage sorting, that is, when the topology of the gene trees may differ from that of the species tree. We show that our technique is statistically consistent under standard stochastic assumptions, that is, it returns the correct tree given sufficiently many unlinked loci. We also show that it can tolerate moderate estimation errors.
  • Keywords
    bioinformatics; estimation theory; genetics; stochastic processes; estimation errors; incomplete lineage sorting; multiple gene trees; multiple loci; phylogeny estimation; stochastic assumptions; Biology and genetics; Incomplete lineage sorting; Probability and Statistics; coalescent process; phylogenetics; population genetics; statistical consistency.; topological concordance; Algorithms; Animals; Chromosome Mapping; Computer Simulation; Evolution; Humans; Linkage Disequilibrium; Models, Genetic; Phylogeny;
  • fLanguage
    English
  • Journal_Title
    Computational Biology and Bioinformatics, IEEE/ACM Transactions on
  • Publisher
    ieee
  • ISSN
    1545-5963
  • Type

    jour

  • DOI
    10.1109/TCBB.2008.66
  • Filename
    4564437