Title :
An intelligent system for vertebrate promoter recognition
Author :
Bajic, Vladimir B. ; Chong, Allen ; Seah, Seng Hong ; Brusic, Vladimir
Abstract :
A promoter, the DNA region encompassing a gene´s transcription start site, largely controls the biological activation of a gene. Dragon Promoter Finder, an advanced system for promoter recognition in vertebrates, uses a collection of models based on multi-sensor integration, signal processing and artificial neural networks. The system minimizes the number of false-positive predictions for various pre-specified sensitivity levels and exhibits several times higher accuracy than other compared systems.
Keywords :
DNA; artificial intelligence; biology computing; genetics; neural nets; pattern recognition; sensitivity; sensor fusion; signal processing; zoology; DNA region; Dragon Promoter Finder; accuracy; artificial neural networks; biological gene activation; false-positive prediction minimization; gene transcription start site; intelligent system; multi-sensor integration; sensitivity levels; signal processing; vertebrate promoter recognition; Artificial neural networks; Bioinformatics; Character recognition; DNA; Face recognition; Intelligent systems; Laboratories; Search methods; Sequences; Signal analysis;
Journal_Title :
Intelligent Systems, IEEE
DOI :
10.1109/MIS.2002.1024754
