DocumentCode :
803799
Title :
Evaluation of clinical PET count rate performance
Author :
Watson, Charles C. ; Casey, Michael E. ; Beyer, Thomas ; Bruckbauer, Thomas ; Townsend, David W. ; Brasse, David
Author_Institution :
CPS Innovations, Knoxville, TN, USA
Volume :
50
Issue :
5
fYear :
2003
Firstpage :
1379
Lastpage :
1385
Abstract :
We propose a new methodology for analyzing clinical positron emission tomography (PET) count rate performance that involves matching net trues (prompts - delayeds) and randoms (delayeds) count rate responses measured on a reference phantom to the actual patient data. We employ these estimated response curves to compute a performance metric closely related to the noise equivalent count rate, as a function of the total singles event rate in the system. From this we can determine the peak performance value relative to the measured performance for any individual acquisition. This maximum performance value depends only on the emitter and attenuator distributions. These peak count rates can be used to derive frame durations for equivalent noise, and correlated with patient weight. We can also determine the singles rate and, thereby, activity necessary to achieve this maximum performance and, based on the known activity in the patient, predict optimal injected doses.
Keywords :
dosimetry; positron emission tomography; clinical PET count rate performance; estimated response curves; frame durations; noise equivalent count rate; optimal injected doses; positron emission tomography; Anthropomorphism; Attenuators; Biomedical imaging; Delay; Imaging phantoms; Measurement standards; Medical diagnostic imaging; Performance analysis; Positron emission tomography; Scattering;
fLanguage :
English
Journal_Title :
Nuclear Science, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9499
Type :
jour
DOI :
10.1109/TNS.2003.817314
Filename :
1236936
Link To Document :
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