Title :
A noninvasive LSO-APD blood radioactivity monitor for PET imaging studies
Author :
Shokouhi, Sepideh ; Stoll, Sean P. ; Villanueva, Azael ; Vaska, Paul ; Schlyer, David J. ; Woody, Craig L. ; Yu, Bo ; O´Connor, Paul ; Pratte, Jean-Francois ; Radeka, Veljko ; Volkow, Nora ; Fowler, Joanna S.
Author_Institution :
Dept. of Biomed. Eng., State Univ. of New York, Stony Brook, NY, USA
Abstract :
A study has been carried out to investigate the possibility of using a pair of LSO + APD detector arrays to obtain a noninvasive measurement of the arterial input function for use in PET. The main focus of this study was to determine the spatial resolution and sensitivity required to obtain a high quality image that would permit a precise determination of the region of interest around the wrist artery. From these data a quantitative arterial input function that has minimal interference from the tissue and vein background can be obtained. The detector arrays were operated in coincidence counting mode to obtain planar images of various phantoms to demonstrate the feasibility of the concept.
Keywords :
avalanche photodiodes; blood; coincidence techniques; phantoms; positron emission tomography; radioactivity measuring apparatus; solid scintillation detectors; PET imaging studies; arterial input function; coincidence counting mode; noninvasive LSO-APD blood radioactivity monitor; phantoms; planar images; positron emission tomography; wrist artery; Arteries; Blood; Detectors; Focusing; Monitoring; Noninvasive treatment; Positron emission tomography; Sensor arrays; Spatial resolution; Wrist;
Journal_Title :
Nuclear Science, IEEE Transactions on
DOI :
10.1109/TNS.2003.817284
