Experimental verification of theoretical in vivo ultrasound heating using cobalt detected magnetic resonance

Author

Smith, N.B. ; Webb, A.G. ; Ellis, D.S. ; O´Brien, William

Author_Institution

Dept. of Electr. & Comput. Eng., Illinois Univ., Urbana, IL, USA

Volume

42

Issue

4

fYear

1995

fDate

7/1/1995 12:00:00 AM

Firstpage

489

Lastpage

491

Abstract

Conventional methods of measuring heating in vivo are invasive and therefore interfere with heat propagation. For the first time, ultrasound-induced temperature increases in living specimens have been estimated theoretically and measured experimentally using a noninvasive technique. In vivo ultrasound-induced temperature increases in the livers of rats show consistent results between: (1) a theoretical ultrasound point-source solution for a measured ultrasound source power of 4.3 W (2/spl deg/C) and (2) a sensitive noninvasive magnetic resonance method with the cobalt (III) nucleus as a probe (2.0/spl plusmn/1.2/spl deg/C).<>

Keywords

biological NMR; biological effects of acoustic radiation; biomedical NMR; biomedical ultrasonics; biothermics; liver; 2 C; 4.3 W; Co; cobalt (III) nucleus; heat propagation; in vivo ultrasound heating; livers; living specimens; magnetic resonance; noninvasive technique; point-source; rats; Estimation theory; Heating; In vivo; Liver; Noninvasive treatment; Rats; Temperature sensors; Time measurement; Ultrasonic imaging; Ultrasonic variables measurement;

fLanguage

English

Journal_Title

Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on

Publisher

ieee

ISSN

0885-3010

Type

jour

DOI

10.1109/58.393091

Filename

393091