DocumentCode :
806377
Title :
Optimal excitation of multiapplicator systems for deep regional hyperthermia
Author :
Boag, Alona ; Leviatan, Yehuda
Author_Institution :
Dept. of Electr. Eng., Technion-Israel Inst. of Technol., Haifa, Israel
Volume :
37
Issue :
10
fYear :
1990
Firstpage :
987
Lastpage :
995
Abstract :
A method is proposed for determining the excitation amplitudes and phases of the elements of electromagnetic multiapplicator systems used for optimizing the specific absorption rate (SAR) distribution around a deep-seated tumor. In this method, the ratio of the power dissipated in the tumor to a weighted summation of the powers supplied to the surrounding regions is optimized. The optimization procedure is combined with a recently proposed technique for analysis of various electromagnetic scattering and interaction problems. The general principle is applied to a two-dimensional problem of a piecewise homogeneous cylinder heated by an array of electric-current filaments placed outside the cylinder. Numerical simulations are performed to check the effectiveness of the approach. The results demonstrate that improved SAR distributions can be achieved using this optimization method. The extension to three-dimensional configurations is discussed.
Keywords :
biomedical equipment; biothermics; electromagnetic fields; numerical analysis; optimisation; radiation therapy; radiofrequency heating; cancer therapy; deep regional hyperthermia; deep seated tumour; electromagnetic multiapplicator systems; excitation amplitudes; numerical simulation; optimal excitation; optimization procedure; phases; piecewise homogeneous cylinder; specific absorption rate distribution; three-dimensional configurations; two-dimensional problem; Cogeneration; Electromagnetic analysis; Electromagnetic scattering; Hyperthermia; Neoplasms; Numerical simulation; Optimization methods; Power supplies; Resistance heating; Specific absorption rate; Electromagnetics; Heat; Humans; Hyperthermia, Induced; Models, Biological; Neoplasms; Tissue Distribution;
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/10.102811
Filename :
102811
Link To Document :
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