Lesion Detection Characteristics of a Focusing Collimator Gamma Camera Coincidence System

The radioisotope response characteristic of a proposed coincidence mode imaging system consisting of an appropriately designed focusing collimator with a gamma camera modified for second moment measurement are calculated for a range of design parameters. Analytic criteria for the detection of small filling defects imbedded in a radioactive medium are developed which directly relate to some of the practical complexities involved in lesion detection. The calculated performances indices of the system suggest that it may be possible to detect lesions significantly smaller than those currently observable.