• DocumentCode
    821948
  • Title

    Metrics for Phylogenetic Networks I: Generalizations of the Robinson-Foulds Metric

  • Author

    Cardona, Gabriel ; Llabré, Mercè ; Rosselló, Francesc ; Valiente, Gabriel

  • Author_Institution
    Univ. of the Balearic Islands, Palma de Mallorca
  • Volume
    6
  • Issue
    1
  • fYear
    2009
  • Firstpage
    46
  • Lastpage
    61
  • Abstract
    The assessment of phylogenetic network reconstruction methods requires the ability to compare phylogenetic networks. This is the first in a series of papers devoted to the analysis and comparison of metrics for tree-child time-consistent phylogenetic networks on the same set of taxa. In this paper, we study three metrics that have already been introduced in the literature: the Robinson-Foulds distance, the tripartition distance, and the mu-distance. They generalize to networks the classical Robinson-Foulds or partition distance for phylogenetic trees. We analyze the behavior of these metrics by studying their least and largest values and when they achieve them. As a by-product of this study, we obtain tight bounds on the size of a tree-child time-consistent phylogenetic network.
  • Keywords
    bioinformatics; genetics; trees (mathematics); Robinson-Foulds distance; Robinson-Foulds metric; mu-distance; phylogenetic network reconstruction; phylogenetic trees; taxonomy; tree-child time consistent phylogenetic networks; tripartitions distance; DNA; Evolution (biology); Genetics; History; Mathematics; Organisms; Phylogeny; Reconstruction algorithms; Sequences; Tree graphs; Biology and genetics; Graph algorithms; Trees; Algorithms; Computational Biology; Evolution, Molecular; Gene Transfer, Horizontal; Hybridization, Genetic; Models, Genetic; Phylogeny; Recombination, Genetic; Time Factors;
  • fLanguage
    English
  • Journal_Title
    Computational Biology and Bioinformatics, IEEE/ACM Transactions on
  • Publisher
    ieee
  • ISSN
    1545-5963
  • Type

    jour

  • DOI
    10.1109/TCBB.2008.70
  • Filename
    4585353