DocumentCode :
825468
Title :
A Programmable 0.18- 
CMOS Electrochemical Sensor Microarray for Biomolecular Detection
Author :
Hassibi, Arjang ; Lee, Thomas H.
Author_Institution :
Center for Integrated Syst., Stanford Univ., CA
Volume :
6
Issue :
6
fYear :
2006
Firstpage :
1380
Lastpage :
1388
Abstract :
A configurable electrochemical sensor microarray system-on-a-chip fabricated in a standard digital 0.18-mum complementary metal-oxide-semiconductor (CMOS) process is presented. Each pixel within this 5times10 array occupies a 160 mumtimes120 mum area and contains a differential electrochemical transducer with a programmable sensor. The sensor has a digitally configurable topology capable of performing different electroanalytical measurements for a variety of affinity-based biomolecular sensing applications. The main modes of operation for this system are impedance spectroscopy, voltammetry, potentiometry, and field-effect sensing
Keywords :
CMOS digital integrated circuits; DNA; biosensors; electrochemical sensors; ion sensitive field effect transistors; molecular biophysics; programmable circuits; proteins; system-on-chip; voltammetry (chemical analysis); 0.18 micron; 120 micron; 160 micron; affinity-based biomolecular sensing applications; biomedical transducers; biomolecular detection; biosensors; de-oxyribonucleic acid microarray; differential electrochemical transducer; digital complementary metal-oxide-semiconductor process; digitally configurable topology; electroanalytical measurements; impedance spectroscopy; ion-sensitive field-effect transistor; potentiometry; programmable CMOS electrochemical sensor microarray; protein microarrays; system-on-a-chip; voltammetry; Biosensors; CMOS image sensors; CMOS process; Impedance; Performance evaluation; Sensor arrays; Sensor systems; System-on-a-chip; Topology; Transducers; Biomedical transducers; biosensors; complementary metal-oxide-semiconductor (CMOS) technology; deoxyribonucleic acid (DNA) microarray; electrochemical analysis; electrodes; impedance spectroscopy; ion-sensitive field-effect transistor (ISFET); protein microarrays; voltammetry;
fLanguage :
English
Journal_Title :
Sensors Journal, IEEE
Publisher :
ieee
ISSN :
1530-437X
Type :
jour
DOI :
10.1109/JSEN.2006.883904
Filename :
4014163
Link To Document :
