Cellular/tissue engineering - Cardiomyoplasty: The prospect of human stem cells

Author

Pedrotty, Dawn M. ; Bursac, Nenad

Author_Institution

Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA

Volume

24

Issue

3

fYear

2005

Firstpage

125

Lastpage

127

Abstract

Currently, the largest ongoing effort in cellular and tissue cardiomyoplasty therapies is the search for a suitable cell source. The following are the desirable attributes of an ideal cell source: 1) autologous (not requiring immune suppression), 2) able to substantially proliferate in vitro, 3) having a similar function when compared to host cardiomyocytes, and 4) able to couple with the host cells electrically and mechanically. A number of cell types have been attempted for cellular and tissue engineering therapies in the heart.

Keywords

bioelectric phenomena; cardiology; cellular biophysics; patient treatment; tissue engineering; cardiomyoplasty; cell source; cellular cardiomyoplasty therapy; cellular engineering; heart; tissue cardiomyoplasty therapy; tissue engineering; tissue engineering therapies; Cardiology; Cells (biology); Clinical trials; Embryo; Heart; Humans; Injuries; Medical treatment; Stem cells; Tissue engineering; Animals; Cardiac Surgical Procedures; Cell Culture Techniques; Cell Differentiation; Heart Diseases; Humans; Muscle Cells; Stem Cell Transplantation; Tissue Engineering;

fLanguage

English

Journal_Title

Engineering in Medicine and Biology Magazine, IEEE

Publisher

ieee

ISSN

0739-5175

Type

jour

DOI

10.1109/MEMB.2005.1436471

Filename

1436471