A Novel Targeted Magnetic Fluid Hyperthermia System Using HTS Coil Array for Tumor Treatment

Author

Linni Jian ; Yujun Shi ; Jianing Liang ; Cheng Liu ; Guoqing Xu

Author_Institution

Shenzhen Inst. of Adv. Technol., Shenzhen, China

Volume

23

Issue

3

fYear

2013

fDate

Jun-13

Firstpage

4400104

Lastpage

4400104

Abstract

This paper presents a concept of a novel targeted magnetic fluid hyperthermia system for tumor treatment. A copper solenoid is engaged to generate an oscillating high-frequency magnetic field in the tumor area to heat the injected nano-particles to kill the tumor cells. In addition, a high temperature superconductor (HTS) coil array consisting of six HTS coils deployed symmetrically in the space surrounding the patient, is used to excite a static magnetic field in the area around the tumor cells to protect the healthy tissues from thermal damage. The design considerations on the HTS coil array and the copper solenoid are introduced. Their performances are quantitatively analyzed by using 3-D finite-element method.

Keywords

biological tissues; biomedical equipment; cellular biophysics; copper; finite element analysis; high-temperature superconductors; hyperthermia; magnetic fluids; nanomedicine; nanoparticles; patient treatment; superconducting coils; superconducting magnets; tumours; 3D finite-element method; Cu; HTS coil array; copper solenoid; healthy tissues; high temperature superconductor coil array; high-frequency magnetic field; nanoparticles; static magnetic field; targeted magnetic fluid hyperthermia system; thermal damage; tumor cells; tumor treatment; Arrays; Coils; High temperature superconductors; Hyperthermia; Magnetic fields; Solenoids; Tumors; Copper solenoid; high temperature superconductor (HTS) coil array; hyperthermia therapy; magnetic fluid hyperthermia; oscillating high-frequency magnetic field; static magnetic field;

fLanguage

English

Journal_Title

Applied Superconductivity, IEEE Transactions on

Publisher

ieee

ISSN

1051-8223

Type

jour

DOI

10.1109/TASC.2012.2230051

Filename

6373704