Title :
A bidomain model of epiretinal stimulation
Author :
Dokos, Socrates ; Suaning, Gregg J. ; Lovell, Nigel H.
Author_Institution :
Graduate Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia
fDate :
6/1/2005 12:00:00 AM
Abstract :
A computational bidomain model of epiretinal stimulation is presented, consisting of a continuum description of active retinal tissue in contact with bulk vitreous fluid. Results from two-electrode and four-electrode bipolar stimulation suggest that a biphasic cathodic-anodic stimulus sequence is effective in providing targeted focal activation of retinal tissue. Undesired secondary activations beneath each electrode return may be eliminated by using multiple returns for each stimulus electrode.
Keywords :
bioelectric potentials; biological tissues; biomedical electrodes; eye; neurophysiology; physiological models; prosthetics; active retinal tissue; bioelectric potentials; biphasic cathodic-anodic stimulus sequence; bipolar stimulation; bulk vitreous fluid; computational bidomain model; epiretinal stimulation; neuroprosthesis; Anisotropic magnetoresistance; Australia; Biomedical engineering; Computational modeling; Conductivity; Electrodes; Extracellular; Neurons; Retina; Voltage; Bioelectric potentials; charge injection; electrodes; modeling; neuroprosthesis; visual system; Action Potentials; Animals; Computer Simulation; Electric Stimulation; Electrodes, Implanted; Humans; Microelectrodes; Models, Neurological; Nerve Net; Retinal Ganglion Cells; Visual Fields; Visual Perception;
Journal_Title :
Neural Systems and Rehabilitation Engineering, IEEE Transactions on
DOI :
10.1109/TNSRE.2005.847390
