Title :
Instrumentation for simultaneous detection of low field NMR and biomagnetic signals
Author :
Matlachov, Andrei N. ; Volegov, Petr L. ; Espy, Michelle A. ; Stolz, Ronny ; Fritzsch, Ludwig ; Zakosarenko, Viatcheslav ; Meyer, Hans-Georg ; Kraus, Robert H., Jr.
Author_Institution :
Los Alamos Nat. Lab., NM, USA
fDate :
6/1/2005 12:00:00 AM
Abstract :
We have built and demonstrated a simple system with open geometry that measures biomagnetic signals such as magnetoencephalogram (MEG), magnetocardiogram (MCG) and magnetomyogram (MMG) simultaneously with low field nuclear magnetic resonance (NMR) free induction decay signals (FID). The system employs LTC SQUID gradiometers and can operate with proton Larmor frequency in the 80 Hz-10 kHz range. A pre-polarizing field of up to 60 mT is generated by resistive coils. Two different types of SQUID gradiometers were used: a tangential thin-film planar first-order gradiometer and an axial second-order gradiometer. The gradiometers were placed inside a fiberglass dewar at about 1 cm distance from a subject. All measurements were performed inside a single-layer magnetic shielded room. This system is the prototype for a system that will ultimately be capable of measuring biomagnetic signals together with magnetic resonance images (MRI).
Keywords :
SQUID magnetometers; biomedical NMR; magnetocardiography; magnetoencephalography; 80 to 10000 Hz; LTC SQUID gradiometers; axial second-order gradiometer; biomagnetic signal detection; biomagnetic signal measurement; biomagnetism; free induction decay signals; low field NMR detection; low field nuclear magnetic resonance; magnetic resonance images; magnetocardiogram; magnetoencephalogram; magnetomyogram; tangential thin-film planar first-order gradiometer; Biomagnetics; Frequency; Geometry; Induction generators; Instruments; Magnetic field measurement; Nuclear magnetic resonance; Nuclear measurements; Protons; SQUIDs; Biomagnetism; FID; NMR; SQUID;
Journal_Title :
Applied Superconductivity, IEEE Transactions on
DOI :
10.1109/TASC.2005.849997