• DocumentCode
    838584
  • Title

    Magnetic stimulation of curved nerves

  • Author

    Rotem, A. ; Moses, E.

  • Author_Institution
    Weizmann Inst. of Sci., Israel
  • Volume
    53
  • Issue
    3
  • fYear
    2006
  • fDate
    3/1/2006 12:00:00 AM
  • Firstpage
    414
  • Lastpage
    420
  • Abstract
    Magnetic stimulation of nerves is attracting increased attention recently, as it has been found to be useful in therapy of neural disorders in humans. In an effort to explain the mechanisms of magnetic stimulation, we focus in this paper on the dependence of magnetic stimulation on neuronal morphology and in particular on the importance of curvature of axonal bundles. Using the theory of passive membrane dynamics, we predict the threshold power (the minimum stimulation power required to initiate an action potential) of specific axonal morphologies. In the experimental section, we show that magnetic stimulation of the frog sciatic nerve follows our theoretical predictions. Furthermore, the voltage length constant of the nerve can be measured based on these results alone.
  • Keywords
    bioelectric potentials; biomagnetism; biomembranes; cellular biophysics; neurophysiology; patient treatment; action potential; axonal bundles; curved nerves; frog sciatic nerve; magnetic stimulation; neural disorders; neuronal morphology; passive membrane dynamics; Biomembranes; Coils; Humans; Length measurement; Magnetic field measurement; Magnetic stimulation; Medical treatment; Morphology; Nerve fibers; Threshold voltage; Curvature; magnetic stimulation; nerve; threshold power; voltage length constant; Action Potentials; Animals; Computer Simulation; Differential Threshold; Electric Stimulation; Magnetics; Models, Neurological; Muscle, Skeletal; Rana ridibunda; Sciatic Nerve;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2005.869770
  • Filename
    1597491