DocumentCode :
841439
Title :
Fixed-Parameter Tractability of the Maximum Agreement Supertree Problem
Author :
Guillemot, Sylvain ; Berry, Vincent
Author_Institution :
Lab. d´´Inf., de Robot. et de Microelectron. de Montpellier (LIRMM), Univ. of Montpellier 2, Montpellier, France
Volume :
7
Issue :
2
fYear :
2010
Firstpage :
342
Lastpage :
353
Abstract :
Given a set L of labels and a collection of rooted trees whose leaves are bijectively labeled by some elements of L, the Maximum Agreement Supertree (SMAST) problem is given as follows: find a tree T on a largest label set L´ ?? L that homeomorphically contains every input tree restricted to L´. The problem has phylogenetic applications to infer supertrees and perform tree congruence analyses. In this paper, we focus on the parameterized complexity of this NP-hard problem, considering different combinations of parameters as well as particular cases. We show that SMAST on k rooted binary trees on a label set of size n can be solved in O((8n)k) time, which is an improvement with respect to the previously known O(n3k2) time algorithm. In this case, we also give an O((2k)pkn2) time algorithm, where p is an upper bound on the number of leaves of L missing in a SMAST solution. This shows that SMAST can be solved efficiently when the input trees are mostly congruent. Then, for the particular case where any triple of leaves is contained in at least one input tree, we give O(4pn3) and O(3.12p + n4) time algorithms, obtaining the first fixed-parameter tractable algorithms on a single parameter for this problem. We also obtain intractability results for several combinations of parameters, thus indicating that it is unlikely that fixed-parameter tractable algorithms can be found in these particular cases.
Keywords :
bioinformatics; computational complexity; evolution (biological); genetics; trees (mathematics); NP hard problem; SMAST problem; bijectively labeled tree leaves; fixed parameter tractability; fixed parameter tractable algorithms; maximum agreement supertree problem; parameterised complexity; phylogenetic applications; rooted binary trees; rooted trees; time complexity; tree congruence analyses; Binary trees; Bioinformatics; Buildings; Data mining; Databases; NP-hard problem; Organisms; Performance analysis; Phylogeny; Upper bound; Phylogenetics; algorithms; maximum agreement supertree; maximum agreement supetree; parameterized complexity; reductions; rooted triples; rooted triples.; Algorithms; Animals; Catarrhini; Computational Biology; Humans; Models, Genetic; Models, Statistical; Phylogeny;
fLanguage :
English
Journal_Title :
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher :
ieee
ISSN :
1545-5963
Type :
jour
DOI :
10.1109/TCBB.2008.93
Filename :
4604656
Link To Document :
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