DocumentCode
84308
Title
The Body Printed: How 3-D Printing Could Change the Face of Modern Medicine?And Why That Future Is Still So Far Away
Author
Fischer, Shannon
Volume
4
Issue
6
fYear
2013
fDate
Nov. 2013
Firstpage
27
Lastpage
31
Abstract
It takes only a few minutes for the NovoGen MMX to print out a chunk of human liver cells. It´s a small chunk, only 4-mm wide and 20 cell layers thick, which wouldn´t do much good in a human patient. But at a cellular level, this tiny swatch of machine-made flesh has all the essential ingredients of an original organ: tight hexagons of hepatocytes and fatty stellate cells and endothelial cells gathered into nascent capillaries. It produces cholesterol, albumin, and detoxifying P450 enzymes. After it is printed, the ensemble can survive for almost an entire week-nearly triple the endurance of classic two-dimensional (2-D) liver cultures.
Keywords
cellular biophysics; enzymes; liver; molecular biophysics; albumin; cholesterol; detoxifying P450 enzymes; endothelial cells; fatty stellate cells; hepatocytes; human liver cells; human patient; machine-made flesh; nascent capillaries; two-dimensional liver cultures; Biomedical imaging; Printing; Three dimensional displays; Animals; Bioprinting; Biotechnology; Humans; Mice; Tissue Engineering;
fLanguage
English
Journal_Title
Pulse, IEEE
Publisher
ieee
ISSN
2154-2287
Type
jour
DOI
10.1109/MPUL.2013.2279618
Filename
6656993
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