• DocumentCode
    84433
  • Title

    A Complete Blood Typing Device for Automatic Agglutination Detection Based on Absorption Spectrophotometry

  • Author

    Fernandes, J. ; Pimenta, Sara ; Soares, Filomena O. ; Minas, Graca

  • Author_Institution
    Dept. of Biomed. Eng., Univ. of Minho, Guimaraes, Portugal
  • Volume
    64
  • Issue
    1
  • fYear
    2015
  • fDate
    Jan. 2015
  • Firstpage
    112
  • Lastpage
    119
  • Abstract
    Blood type determination is an important clinical test that should be performed before any blood transfusion. However, in emergency situations, due to the patient´s condition, there may not be enough time to determine the patient´s blood type. In these cases, the O negative blood type is administered, because it causes less incompatibility risk to the patient. This paper presents a low-cost and portable device for ABO, Rh phenotype, reverse, and Cross-matching human blood typing, based on a spectrophotometric approach of the agglutination detection, with a fast response time (results in <;5 min). These features allow the device operation in mobile emergency units, outside conventional clinical laboratories, and close to the patient. It avoids the risk of incompatibility between the donor´s and receptor´s blood, improving the quality in healthcare services.
  • Keywords
    biomedical equipment; blood; health care; ABO phenotype; O negative blood type; Rh phenotype; absorption spectrophotometry; agglutination detection; blood incompatibility; blood transfusion; blood typing device; clinical test; crossmatching human blood typing; healthcare services; mobile emergency units; patient condition; reverse blood typing; spectrophotometric approach; Cells (biology); Light emitting diodes; Light sources; Performance evaluation; Protocols; Red blood cells; Agglutination detection; blood incompatibility; blood typing; portable device; spectrophotometric approach; spectrophotometric approach.;
  • fLanguage
    English
  • Journal_Title
    Instrumentation and Measurement, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9456
  • Type

    jour

  • DOI
    10.1109/TIM.2014.2331428
  • Filename
    6850053