Size Dependent In-Vitro Heating With Polyethylene Glycol Coated Magnetic Nanoparticles

Magnetic nanoparticles represent a nanotechnology for the treatment of cancer as a result of the localized thermal gradients produced in response to an oscillating magnetic field. Using a sodium borohydride reduction of ferrous chloride in the presence of carboxyl terminated polyethylene glycol this study looks at the contribution of particle size to the achievable temperature using a 500 kHz excitation field. By magnetically separating the as-synthesized sample it was found that the smaller particles within the sample are more effective heating elements.