Title :
Co-Ni-W-P Magnetic Films Electrolessly Deposited on Nitinol and the Application in Magnetically Targeted Therapy
Author :
Cheng, Haibin ; Xu, Shuai ; Zou, Shengquan ; Zhang, Qingjie ; Zheng, Jianwei ; Zhao, Wenyu ; Guan, Jianguo ; Sun, Zhigang
Author_Institution :
State Key Lab. of Adv. Technol. for Mater. Synthesis & Process., Wuhan Univ. of Technol.
fDate :
6/1/2007 12:00:00 AM
Abstract :
Co-Ni-W-P magnetic films were electrolessly deposited on the nitinol wires. Their composition, microstructure, and magnetic properties were characterized by EDS, FESEM, and VSM. Their application in magnetically targeted therapy was investigated on animals. It was found that their composition and surface morphology can be controlled by the bath pH which can strongly influence the Hc, Mr, and BHmax. The magnetic nitinol wires with the Co-Ni-W-P films, combining with the magnetic nanoparticles containing 5-FU, were confirmed to be able to effectively inhibit the growth of tumors.
Keywords :
X-ray chemical analysis; biomagnetism; cobalt alloys; crystal structure; electroless deposition; magnetic particles; magnetic thin films; nanobiotechnology; nanoparticles; nickel alloys; pH; phosphorus alloys; radiation therapy; scanning electron microscopy; surface morphology; titanium alloys; tumours; tungsten alloys; CoNiWP; EDS; FESEM; NiTi; VSM; composition; electroless deposition; magnetic films; magnetic nanoparticles; magnetic properties; magnetically targeted therapy; microstructure; nitinol wires; pH; surface morphology; tumours; Magnetic films; Magnetic materials; Magnetic properties; Materials science and technology; Medical treatment; Microstructure; Neoplasms; Substrates; Surface morphology; Wires; Co-Ni-W-P magnetic film; magnetic property; magnetically targeted therapy; microstructure;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2007.893851
