Preparation, Characterization and in vitro Toxicity Test of Magnetic Nanoparticle-Based Drug Delivery System to Hyperthermia of Biological Tissues

The goals of this study were first to prepare and second to test albumin-based beads containing maghemite nanoparticles dispersed on them. Incorporation of maghemite nanoparticles in the albumin-based template, allowing full control of the magnetic content, was accomplished by adding ionic magnetic fluid to the albumin suspension, following heat denaturation. The material evaluation was performed using Zeta potential measurements and scanning electron microscopy from one side and by investigating the cell activity on the other hand.