Title :
Fast Nonparametric Clustering of Structured Time-Series
Author :
Hensman, James ; Rattray, Magnus ; Lawrence, Neil D.
Author_Institution :
Department of Computer Science and Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, South Yorkshire, United Kingdom
Abstract :
In this publication, we combine two Bayesian nonparametric models: the Gaussian Process (GP) and the Dirichlet Process (DP). Our innovation in the GP model is to introduce a variation on the GP prior which enables us to model structured time-series data, i.e., data containing groups where we wish to model inter- and intra-group variability. Our innovation in the DP model is an implementation of a new fast collapsed variational inference procedure which enables us to optimize our variational approximation significantly faster than standard VB approaches. In a biological time series application we show how our model better captures salient features of the data, leading to better consistency with existing biological classifications, while the associated inference algorithm provides a significant speed-up over EM-based variational inference.
Keywords :
Biological system modeling; Computational modeling; Data models; Gaussian processes; Optimization; Time series analysis; Vectors; Gaussian processes; Variational Bayes; gene expression; structured time series;
Journal_Title :
Pattern Analysis and Machine Intelligence, IEEE Transactions on
DOI :
10.1109/TPAMI.2014.2318711