• DocumentCode
    86191
  • Title

    Fast Nonparametric Clustering of Structured Time-Series

  • Author

    Hensman, James ; Rattray, Magnus ; Lawrence, Neil D.

  • Author_Institution
    Department of Computer Science and Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, South Yorkshire, United Kingdom
  • Volume
    37
  • Issue
    2
  • fYear
    2015
  • fDate
    Feb. 1 2015
  • Firstpage
    383
  • Lastpage
    393
  • Abstract
    In this publication, we combine two Bayesian nonparametric models: the Gaussian Process (GP) and the Dirichlet Process (DP). Our innovation in the GP model is to introduce a variation on the GP prior which enables us to model structured time-series data, i.e., data containing groups where we wish to model inter- and intra-group variability. Our innovation in the DP model is an implementation of a new fast collapsed variational inference procedure which enables us to optimize our variational approximation significantly faster than standard VB approaches. In a biological time series application we show how our model better captures salient features of the data, leading to better consistency with existing biological classifications, while the associated inference algorithm provides a significant speed-up over EM-based variational inference.
  • Keywords
    Biological system modeling; Computational modeling; Data models; Gaussian processes; Optimization; Time series analysis; Vectors; Gaussian processes; Variational Bayes; gene expression; structured time series;
  • fLanguage
    English
  • Journal_Title
    Pattern Analysis and Machine Intelligence, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0162-8828
  • Type

    jour

  • DOI
    10.1109/TPAMI.2014.2318711
  • Filename
    6802369