• DocumentCode
    86531
  • Title

    HEp-2 Cell Classification Using Shape Index Histograms With Donut-Shaped Spatial Pooling

  • Author

    Larsen, Anders Boesen Lindbo ; Vestergaard, Jacob Schack ; Larsen, Rasmus

  • Author_Institution
    Dept. of Appl. Math. & Comput. Sci., Tech. Univ. of Denmark, Lyngby, Denmark
  • Volume
    33
  • Issue
    7
  • fYear
    2014
  • fDate
    Jul-14
  • Firstpage
    1573
  • Lastpage
    1580
  • Abstract
    We present a new method for automatic classification of indirect immunoflourescence images of HEp-2 cells into different staining pattern classes. Our method is based on a new texture measure called shape index histograms that captures second-order image structure at multiple scales. Moreover, we introduce a spatial decomposition scheme which is radially symmetric and suitable for cell images. The spatial decomposition is performed using donut-shaped pooling regions of varying sizes when gathering histogram contributions. We evaluate our method using both the ICIP 2013 and the ICPR 2012 competition datasets. Our results show that shape index histograms are superior to other popular texture descriptors for HEp-2 cell classification. Moreover, when comparing to other automated systems for HEp-2 cell classification we show that shape index histograms are very competitive; especially considering the relatively low complexity of the method.
  • Keywords
    biomedical optical imaging; cellular biophysics; fluorescence; image classification; image texture; medical image processing; HEp-2 cell classification method; cell image classification; donut-shaped pooling region; donut-shaped spatial pooling; indirect immunoflourescence image; popular texture descriptor; second-order image structure; shape index histogram; spatial decomposition scheme; texture measure; Accuracy; Feature extraction; Histograms; Indexes; Shape; Shape measurement; Vectors; Cell classification; feature histograms; indirect immunofluorescence; shape index; spatial pooling; texture description;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/TMI.2014.2318434
  • Filename
    6802403