Title :
Modeling of skin tissue ablation by nanosecond pulses from ultraviolet to near-infrared and comparison with experimental results
Author :
Fang, Qiyin ; Hu, Xin-Hua
Author_Institution :
Dept. of Phys., East Carolina Univ., Greenville, NC, USA
Abstract :
Comprehension of biological tissue ablation by short laser pulses in a broad optical spectrum is of fundamental importance to the understanding of laser-tissue interaction and advancing surgical applications of lasers. We report a new plasma ablation model in which the chromophore ionization pathway is incorporated to explain the skin tissue ablation by nanosecond laser pulses from ultraviolet to near-infrared. A rate equation is solved to examine the effects of chromophore, cascade, and multiphoton ionization on the optical breakdown of the tissue. The wavelength and spot size dependence of the breakdown thresholds have been measured and agreements have been found between the calculated and measured results.
Keywords :
biological effects of laser radiation; biological effects of ultraviolet radiation; biothermics; laser ablation; laser applications in medicine; multiphoton processes; skin; surgery; breakdown threshold; broad optical spectrum; chromophore ionization pathway; laser ablation; laser-tissue interaction; multiphoton ionization; nanosecond laser pulses; near-infrared laser pulses; optical breakdown; plasma ablation model; rate equation; skin tissue ablation; surgical applications; transient heating; ultraviolet laser pulses; Biological system modeling; Biomedical optical imaging; Electric breakdown; Ionization; Laser ablation; Laser modes; Nanobioscience; Optical pulses; Quantum cascade lasers; Skin;
Journal_Title :
Quantum Electronics, IEEE Journal of
DOI :
10.1109/JQE.2003.820837