• DocumentCode
    873492
  • Title

    A Statistical Analysis of Count Normalization Methods Used in Positron-Emission Tomography

  • Author

    Holmes, Timothy J. ; Snyder, Donald L. ; Ficke, David C.

  • Author_Institution
    Institute for Biomedical Computing, Department of Electrical Engineering, and Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri 63110
  • Volume
    31
  • Issue
    1
  • fYear
    1984
  • Firstpage
    521
  • Lastpage
    526
  • Abstract
    As part of the Positron-Emission Tomography (PET) [1] reconstruction process, annihilation counts are normalized for photon absorption, detector efficiency and detector-pair duty-cycle. Several normalization methods of time-of-flight and conventional systems are analyzed mathematically for count bias and variance. The results of the study have some implications on hardware and software complexity and on image noise and distortion.
  • Keywords
    Biomedical computing; Biomedical measurements; Detectors; Electromagnetic wave absorption; Image reconstruction; Instruments; Position measurement; Positron emission tomography; Radiology; Statistical analysis;
  • fLanguage
    English
  • Journal_Title
    Nuclear Science, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9499
  • Type

    jour

  • DOI
    10.1109/TNS.1984.4333311
  • Filename
    4333311