• DocumentCode
    884499
  • Title

    Chrono-coherent imaging for medicine

  • Author

    Spears, Kenneth G. ; Serafin, Jenifer ; Abramson, Nils H. ; Zhu, Xinming ; Bjelkhagen, Hans

  • Author_Institution
    Northwestern Univ., Evanston, IL, USA
  • Volume
    36
  • Issue
    12
  • fYear
    1989
  • Firstpage
    1210
  • Lastpage
    1221
  • Abstract
    A method for imaging with visible and near-visible light inside media, such as tissues, which have strong light scattering is described. The chrono-coherent imaging (CCI) method is demonstrated for a transmission geometry where an absorbing object is completely hidden from normal visual observation by scattered light. The resultant images are most similar to X-rays, with cumulative transmission showing absorption features and refractive index differences in the media. Laser coherence properties, coherence measurements, the relation of CCI to light-in-flight holography, holographic film properties relevant to CCI, a particular optical setup for CCI, the results of a demonstration experiment imaging an absorbing object hidden by light scattering, and an experiment to estimate the clinical applicability of CCI are discussed.
  • Keywords
    holography; laser applications in medicine; light absorption; light coherence; light scattering; patient diagnosis; refractive index; X-rays; absorbing object; absorption features; chrono-coherent imaging; clinical applicability; coherence measurements; cumulative transmission; holographic film properties; inside media; internally invisible object; laser coherence properties; light-in-flight holography; medicine; refractive index differences; resultant images; strong light scattering; tissues; transmission geometry; visible light imaging; Biomedical imaging; Electromagnetic wave absorption; Geometrical optics; Holographic optical components; Light scattering; Optical films; Optical imaging; Optical scattering; Radiofrequency interference; X-ray scattering; Diagnostic Imaging; Holography; Lasers; Mathematics; Models, Structural; Optics;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/10.42116
  • Filename
    42116