Title :
Chrono-coherent imaging for medicine
Author :
Spears, Kenneth G. ; Serafin, Jenifer ; Abramson, Nils H. ; Zhu, Xinming ; Bjelkhagen, Hans
Author_Institution :
Northwestern Univ., Evanston, IL, USA
Abstract :
A method for imaging with visible and near-visible light inside media, such as tissues, which have strong light scattering is described. The chrono-coherent imaging (CCI) method is demonstrated for a transmission geometry where an absorbing object is completely hidden from normal visual observation by scattered light. The resultant images are most similar to X-rays, with cumulative transmission showing absorption features and refractive index differences in the media. Laser coherence properties, coherence measurements, the relation of CCI to light-in-flight holography, holographic film properties relevant to CCI, a particular optical setup for CCI, the results of a demonstration experiment imaging an absorbing object hidden by light scattering, and an experiment to estimate the clinical applicability of CCI are discussed.
Keywords :
holography; laser applications in medicine; light absorption; light coherence; light scattering; patient diagnosis; refractive index; X-rays; absorbing object; absorption features; chrono-coherent imaging; clinical applicability; coherence measurements; cumulative transmission; holographic film properties; inside media; internally invisible object; laser coherence properties; light-in-flight holography; medicine; refractive index differences; resultant images; strong light scattering; tissues; transmission geometry; visible light imaging; Biomedical imaging; Electromagnetic wave absorption; Geometrical optics; Holographic optical components; Light scattering; Optical films; Optical imaging; Optical scattering; Radiofrequency interference; X-ray scattering; Diagnostic Imaging; Holography; Lasers; Mathematics; Models, Structural; Optics;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
