Title :
Computer-Aided Diagnosis Software for Hypertensive Risk Determination Through Fundus Image Processing
Author :
Morales, S. ; Naranjo, V. ; Navea, Amparo ; Alcaniz, Mariano
Author_Institution :
Inst. Interuniversitario de Investig. en Bioingenieria y Tecnol. Orientada al Ser Humano, Univ. Politec. de Valencia, Valencia, Spain
Abstract :
The goal of the software proposed in this paper is to assist ophthalmologists in diagnosis and disease prevention, helping them to determine cardiovascular risk or other diseases where the vessels can be altered, as well as to monitor the pathology progression and response to different treatments. The performance of the tool has been evaluated by means of a double-blind study where its sensitivity, specificity, and reproducibility to discriminate between health fundus (without cardiovascular risk) and hypertensive patients has been calculated in contrast to an expert ophthalmologist opinion obtained through a visual inspection of the fundus image. An improvement of almost 20% has been achieved comparing the system results with the clinical visual classification.
Keywords :
biomedical optical imaging; blood vessels; cardiovascular system; diseases; eye; image classification; medical image processing; cardiovascular diseases; clinical visual classification; computer-aided diagnosis software; double-blind study; fundus image processing; hypertensive patients; hypertensive risk determination; pathology progression monitoring; vessels; Bifurcation; Biomedical image processing; Computer aided diagnosis; Hypertension; Retinal vessels; Software; Bifurcation angles; hypertension; retinal vascular tree; retinal vessels; vessel caliber;
Journal_Title :
Biomedical and Health Informatics, IEEE Journal of
DOI :
10.1109/JBHI.2014.2337960
