Computer-Aided Diagnosis Software for Hypertensive Risk Determination Through Fundus Image Processing

Author

Morales, S. ; Naranjo, V. ; Navea, Amparo ; Alcaniz, Mariano

Author_Institution

Inst. Interuniversitario de Investig. en Bioingenieria y Tecnol. Orientada al Ser Humano, Univ. Politec. de Valencia, Valencia, Spain

Volume

18

Issue

6

fYear

2014

fDate

Nov. 2014

Firstpage

1757

Lastpage

1763

Abstract

The goal of the software proposed in this paper is to assist ophthalmologists in diagnosis and disease prevention, helping them to determine cardiovascular risk or other diseases where the vessels can be altered, as well as to monitor the pathology progression and response to different treatments. The performance of the tool has been evaluated by means of a double-blind study where its sensitivity, specificity, and reproducibility to discriminate between health fundus (without cardiovascular risk) and hypertensive patients has been calculated in contrast to an expert ophthalmologist opinion obtained through a visual inspection of the fundus image. An improvement of almost 20% has been achieved comparing the system results with the clinical visual classification.

Keywords

biomedical optical imaging; blood vessels; cardiovascular system; diseases; eye; image classification; medical image processing; cardiovascular diseases; clinical visual classification; computer-aided diagnosis software; double-blind study; fundus image processing; hypertensive patients; hypertensive risk determination; pathology progression monitoring; vessels; Bifurcation; Biomedical image processing; Computer aided diagnosis; Hypertension; Retinal vessels; Software; Bifurcation angles; hypertension; retinal vascular tree; retinal vessels; vessel caliber;

fLanguage

English

Journal_Title

Biomedical and Health Informatics, IEEE Journal of

Publisher

ieee

ISSN

2168-2194

Type

jour

DOI

10.1109/JBHI.2014.2337960

Filename

6851867