DocumentCode :
888998
Title :
Improved safety and efficacy in adaptive control of arterial blood pressure through the use of a supervisor
Author :
Martin, James F. ; Schneider, Alan M. ; Quinn, Michael L. ; Smith, Ty N.
Author_Institution :
California Univ., San Diego, CA, USA
Volume :
39
Issue :
4
fYear :
1992
fDate :
4/1/1992 12:00:00 AM
Firstpage :
381
Lastpage :
388
Abstract :
A dual approach to adaptive control of arterial blood pressure using sodium nitroprusside is presented. In the clinical environment, a controller must be aggressive to achieve specific step response characteristics (less than 10 min setting time, less than 10 mm Hg overshoot), yet conservative enough to prevent overreactions to large disturbances, which are common in both the operating room and the intensive care unit. These mutually exclusive requirements make it difficult to design a closed-loop controller for this environment. To prevent possible overreactions while maintaining proper step response, an aggressive adaptive controller has been designed to achieve the desired step response, and a supervisor has been designed around the adaptive controller to limit potential overreactions in the presence of disturbances. Simulations and dog experiments demonstrate the potential for increased safety and efficacy using this dual approach to the control of a complex physiological system.
Keywords :
adaptive control; haemodynamics; patient treatment; pressure control; aggressive adaptive controller; arterial blood pressure; clinical environment; complex physiological system; dog experiments; efficacy; intensive care unit; operating room; safety; simulations; sodium nitroprusside; step response characteristics; supervisor; Adaptive control; Animals; Arterial blood pressure; Blood pressure; Helium; Mercury (metals); Pressure control; Programmable control; Safety; Testing; Animals; Artifacts; Computer Simulation; Dogs; Feedback; Hypertension; Infusion Pumps; Nitroprusside; Safety; Therapy, Computer-Assisted;
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/10.126610
Filename :
126610
Link To Document :
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