• DocumentCode
    893156
  • Title

    Refractometric Sensors for Lab-on-a-Chip Based on Optical Ring Resonators

  • Author

    White, Ian M. ; Zhu, Hongying ; Suter, Jonathan D. ; Hanumegowda, Niranjan M. ; Oveys, Hesam ; Zourob, Mohammed ; Fan, Xudong

  • Author_Institution
    Dept. of Biol. Eng., Missouri Univ., Columbia, MO
  • Volume
    7
  • Issue
    1
  • fYear
    2007
  • Firstpage
    28
  • Lastpage
    35
  • Abstract
    We demonstrate refractive index measurement of liquids using two sensor system designs, both based on microring resonators. Evanescent sensors based on microrings utilize the resonating nature of the light to dramatically decrease the required size and sample consumption volume, which are requirements of lab-on-a-chip sensor systems. The first design, which utilizes an optical microsphere, exhibits a sensitivity of 30 nm/RIU and a resulting detection limit on the order of 10-7 RIU. The second approach is a novel design called a liquid core optical ring resonator (LCORR). This concept uses a quartz capillary as the fluidics and as the ring resonator and achieves a sensitivity of 16.1 nm/RIU. The detection limit of this system is around 5times10-6 RIU. Both of these systems have the potential to be incorporated with advanced microfluidic systems for lab-on-a-chip applications. In particular, the LCORR combines high sensitivity, performance stability, and microfluidic compatibility, making it an excellent choice for lab-on-a-chip development
  • Keywords
    lab-on-a-chip; microfluidics; micromechanical resonators; optical resonators; optical sensors; refractive index measurement; whispering gallery modes; lab-on-a-chip sensor; label-free sensing; liquid core optical ring resonator; microfluidic systems; microring resonators; optical microsphere; quartz capillary; refractive index measurement; refractometric sensors; whispering gallery modes; Lab-on-a-chip; Liquids; Microfluidics; Optical design; Optical refraction; Optical resonators; Optical ring resonators; Optical sensors; Refractive index; Sensor systems; Label-free sensing; optical ring resonator; refractive index; whispering gallery modes;
  • fLanguage
    English
  • Journal_Title
    Sensors Journal, IEEE
  • Publisher
    ieee
  • ISSN
    1530-437X
  • Type

    jour

  • DOI
    10.1109/JSEN.2006.887927
  • Filename
    4039329