Title :
A Preliminary Evaluation of the Use of the EM Algorithm for Estimating Parameters in Dynamic Tracer-Studies
Author :
Ollinger, John M. ; Snyder, Donald L.
Author_Institution :
Department of Electrical Engineering and Institute for Biomedical Computing Washington University St. Louis, Missouri 63130
Abstract :
The iterative, estimation-maximization algorithm for numerically generating maximum-likelihood estimates of parameters is investigated for use in processing data acquired in dynamic radioactive-tracer studies. This algorithm compared favorably to the best known alternative.
Keywords :
Biomedical computing; Convergence; Image reconstruction; Iterative algorithms; Iterative methods; Maximum likelihood estimation; Parameter estimation; Poisson equations; Signal resolution; Spatial resolution;
Journal_Title :
Nuclear Science, IEEE Transactions on
DOI :
10.1109/TNS.1985.4336954
