Title :
Discrimination of Breast Tumors in Ultrasonic Images Using an Ensemble Classifier Based on the AdaBoost Algorithm With Feature Selection
Author :
Takemura, Atsushi ; Shimizu, Akinobu ; Hamamoto, Kazuhiko
Author_Institution :
Inst. of Symbiotic Sci. & Technol., Tokyo Univ. of Agric. & Technol., Koganei, Japan
fDate :
3/1/2010 12:00:00 AM
Abstract :
This paper proposes a novel algorithm to estimate a log-compressed K distribution parameter and presents an algorithm to discriminate breast tumors in ultrasonic images. We computed a total of 208 features for discrimination, including those based on a parameter of a log-compressed K-distribution, which quantifies the homogeneity of the echo pattern in the tumor, but is influenced by compression parameters in the ultrasonic device. The proposed algorithm estimates the parameter of the log-compressed K-distribution in a manner free from this influence. To quantify irregularities in tumor shape, pattern-spectrum-based features were newly developed in this paper. The discrimination process uses an ensemble classifier trained by a multiclass AdaBoost learning algorithm (AdaBoost.M2), combined with a sequential feature-selection process. A 10-fold cross-validation test validated the performance, and the results were compared with those of a Mahalanobis distance-based classifier and a multiclass support vector machine. A total of 200 carcinomas, 50 fibroadenomas, and 50 cysts were used in the experiments. This paper demonstrates that the combination of a classifier trained by AdaBoost.M2 and features based on the estimated parameter of a log-compressed K-distribution, as well as those of the pattern spectrum, are useful for the discrimination of tumors.
Keywords :
biological organs; biomedical ultrasonics; cancer; image classification; log normal distribution; medical image processing; tumours; breast tumor; carcinomas; compression parameters; discrimination process; echo pattern homogeneity; ensemble classifier; fibroadenomas; log-compressed K distribution parameter; multiclass AdaBoost learning algorithm; pattern spectrum; sequential feature selection; ultrasonic imaging; Breast neoplasms; Breast tumors; Cancer; Image coding; Malignant tumors; Parameter estimation; Shape; Support vector machine classification; Support vector machines; Ultrasonic imaging; AdaBoost.M2; breast tumor; differential diagnosis; log-compressed K-distribution; support vector machine (SVM); ultrasonic image; Algorithms; Artificial Intelligence; Breast Cyst; Breast Neoplasms; Carcinoma; Databases, Factual; Female; Fibroadenoma; Humans; Image Interpretation, Computer-Assisted; Reproducibility of Results; Ultrasonography, Mammary;
Journal_Title :
Medical Imaging, IEEE Transactions on
DOI :
10.1109/TMI.2009.2022630