This paper treats the problem of estimating a signal

in the presence of noise

where

and

are independent nonstationary Gaussian processes. Specifically, we present the maximum likelihood and the minimum mean-square estimates of

for each

, by observing the entire signal-plus-noise waveform

during the interval
![[T_{1}, T_{2}]](/images/tex/8030.gif)
. Under the condition that the signal cannot be detected perfectly in the presence of noise, we explicilyty prove that both estimates, denoted by

, are given by

, the conditional expectation of

given

. With the use of simultaneously orthogonal expansions of

and

, we further obtain explicit expressions in the form of infinite series for

and

, the minimum mean-square error. Moreover, if the integral equation

admits a formal solution

, then

and

have the closed-form expressions

where

and

are the covariances of

and

, respectively, and

is the largest integer for which the

th partial derivatives of the covariances are continuous. The last result is a generalization of the classical Wiener filtering theory for stationary processes, and it is valid without the condition of imperfect detection if existence of the formal solution is assumed instead. Finally, we exhibit a general solution of the integral equation in the case where both

and

have rational power spectra.