Title :
Cryo-electron tomography of biological specimens
Author :
Leis, Andrew P. ; Beck, Martin ; Gruska, Manuela ; Best, Christoph ; Hegerl, Reiner ; Baumeister, Wolfgang ; Leis, John W.
Author_Institution :
Max-Planck-Inst. of Biochem., Munchen, Germany
fDate :
5/1/2006 12:00:00 AM
Abstract :
This paper describes the important considerations in cryo-electron tomography (CET) of biological specimens and identifies the areas where digital signal processing can make a decisive contribution.
Keywords :
X-ray crystallography; computerised tomography; image denoising; image resolution; image segmentation; medical image processing; 3D segmentation; 3D structure visualization; X-ray crystallography; automated tomography; biological specimens; cryoelectron tomography; denoising; digital signal processing; electron density maps; high-resolution structures correlation; molecular visualization; Biological tissues; Crystallography; Digital signal processing; Electron microscopy; Image reconstruction; Signal processing algorithms; Tomography; Transmission electron microscopy; Visualization; X-ray imaging;
Journal_Title :
Signal Processing Magazine, IEEE
DOI :
10.1109/MSP.2006.1628882