Matched filter estimation of serial blood vessel diameters from video images

A method for making a contiguous series of blood vessel diameter estimates from digitized images is proposed. It makes use of a vessel intensity profile model based on the vessel geometry and the physics of the imaging process, providing estimates of far greater accuracy than previously obtained. A variety of techniques are used to reduce the computational demand. The method includes the generation of measurement estimation error, which is important in determining total vessel patency as well as providing a basic measure of diameter estimate accuracy