Title :
Theoretical assessment of FePt nanoparticles as heating elements for magnetic hyperthermia
Author :
Maenosono, Shinya ; Saita, Soichiro
Author_Institution :
Dept. of Chem. Syst. Eng., Univ. of Tokyo
fDate :
6/1/2006 12:00:00 AM
Abstract :
FePt magnetic nanoparticles (MNPs) are expected to be a high-performance nanoheater for magnetic hyperthermia because of their high Curie temperature, high saturation magnetization, and high chemical stability. Here, we present a theoretical performance assessment of chemically disordered fcc-phase FePt MNPs. We calculate heat generation and heat transfer in the tissue when an MNP-loaded tumor is placed on an external alternating magnetic field. For comparison, we estimate the performances of magnetite, maghemite, FeCo, and L10-phase FePt MNPs. We find that an fcc FePt MNP has a superior ability in magnetic hyperthermia
Keywords :
biothermics; cancer; heat transfer; hyperthermia; iron alloys; magnetic particles; nanoparticles; platinum alloys; tumours; FePt; bioheat transfer equation; cancer treatment; magnetic hyperthermia; magnetic nanoparticles; Chemical elements; Heat transfer; Heating; Hyperthermia; Magnetic fields; Nanoparticles; Neoplasms; Saturation magnetization; Stability; Temperature; Bioheat transfer equation; cancer treatment; hyperthermia; iron-platinum nanoparticle;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2006.872198
