• DocumentCode
    941641
  • Title

    Optical properties of wounds: diabetic versus healthy tissue

  • Author

    Papazoglou, Elisabeth S. ; Weingarten, Michael S. ; Zubkov, Leonid ; Zhu, Linda ; Tyagi, Som ; Pourrezaei, Kambiz

  • Author_Institution
    Sch. of Biomed. Eng. & Sci., Drexel Univ., Philadelphia, PA, USA
  • Volume
    53
  • Issue
    6
  • fYear
    2006
  • fDate
    6/1/2006 12:00:00 AM
  • Firstpage
    1047
  • Lastpage
    1055
  • Abstract
    Diffuse photon density wave (DPDW) methodology at Near Infrared frequencies has been used to calculate absorption and scattering from wounds of healthy and diabetic rats. The diffusion equation for semi-infinite media is being used for calculating the absorption and scattering coefficients based on measurements of phase and amplitude with a frequency domain device. Differences observed during the course of healing in the two populations can be correlated to the delayed healing observed in diabetics. These results are encouraging and further work will focus on the implementation of this device to the clinical setting as a monitoring tool in chronic diabetic wounds.
  • Keywords
    absorption coefficients; bio-optics; biological tissues; biomedical equipment; diseases; patient monitoring; absorption coefficient; diabetic tissue; diffuse photon density wave; diffusion equation; frequency domain device; healthy tissue; monitoring tool; near infrared frequencies; optical properties; rats; scattering coefficient; semi-infinite media; wounds; Diabetes; Electromagnetic wave absorption; Equations; Frequency domain analysis; Frequency measurement; Optical scattering; Particle scattering; Phase measurement; Rats; Wounds; Diabetic wounds; diffuse photon density wave; near infrared spectroscopy (NIRS); Animals; Diabetes Complications; Diagnosis, Computer-Assisted; Equipment Design; Equipment Failure Analysis; Feasibility Studies; Female; Light; Rats; Spectrophotometry, Infrared; Wound Healing; Wounds, Penetrating;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2006.873541
  • Filename
    1634499