Title :
Implementation of simultaneous attenuation and detector response correction in SPECT
Author :
Tsui, Benjamin M W ; Hu, Hong-Bin ; Gilland, David R. ; Gullberg, Grant T.
Author_Institution :
Dept. of Radiol. & Curriculum in Biomed. Eng., North Carolina Univ., Chapel Hill, NC, USA
Abstract :
Simultaneous correction of nonuniform attenuation and detector response was implemented in single-photon-emission computed tomography (SPECT) image reconstruction. A ray-driven projector-backprojector that exactly models attenuation in the reconstructed image slice and the spatially variant detector response was developed and used in the iterative maximum-likelihood algorithm for the correction. A computer-generated heart-lung phantom was used in simulation studies to compare the simultaneous correction method with an intrinsic attenuation correction method using a smoothing filter, and intrinsic attenuation correction method using a deconvolution filter, and a modified Chang attenuation correction method using a nonuniform attenuation distribution. The results demonstrate that the present method provides more-accurate quantitation and superior image quality.<>
Keywords :
computerised tomography; radioisotope scanning and imaging; SPECT; deconvolution filter; detector response correction; heart-lung phantom; iterative maximum-likelihood algorithm; modified Chang attenuation correction method; nonuniform attenuation; ray-driven projector-backprojector; reconstructed image slice; single-photon-emission computed tomography; smoothing filter; spatially variant detector response; Attenuation; Computational modeling; Computed tomography; Detectors; Distributed computing; Filters; Image reconstruction; Imaging phantoms; Iterative algorithms; Maximum likelihood detection;
Journal_Title :
Nuclear Science, IEEE Transactions on
