Title :
An integrated system for real-time detection of stiff masses with a single compression
Author :
Fahmy, Ahmed S. ; Krieger, Axel ; Osman, Nael F.
Author_Institution :
Dept. of Electr. & Comput. Eng., Johns Hopkins Univ., Baltimore, MD, USA
fDate :
7/1/2006 12:00:00 AM
Abstract :
An integrated system is proposed for real-time imaging of tissue deformation in response to externally applied mechanical compression. The purpose of the system is to noninvasively detect tissue lesions based on their stiffness. The method includes applying external compression to the examined subject and acquiring magnetic resonance strain-encoded images using a real-time pulse sequence. In the proposed system, only a single compression is necessary to obtain a two-dimensional map of tissue deformation in a slice, eliminating the need for a complicated compressing device. The system was built and validated using phantom experiments.
Keywords :
biomechanics; biomedical MRI; deformation; phantoms; tumours; integrated system; magnetic resonance strain-encoded images; noninvasive tissue lesion detection; phantom; real-time detection; real-time imaging; real-time pulse sequence; single mechanical compression; stiff masses; stiffness; tissue deformation; Biomedical engineering; Biomedical measurements; Breast neoplasms; Encoding; Image coding; Magnetic resonance imaging; Real time systems; Tagging; Ultrasonic imaging; Ultrasonic variables measurement; Magnetic resonance imaging; strain encoding; tagging; tissue deformation; Compressive Strength; Computer Simulation; Computer Systems; Connective Tissue; Elasticity; Equipment Design; Equipment Failure Analysis; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Models, Biological; Phantoms, Imaging; Physical Stimulation; Reproducibility of Results; Sensitivity and Specificity; Stress, Mechanical; Systems Integration;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2006.873690
