DocumentCode :
983069
Title :
Real-time detection of microbial contamination
Author :
Kim, Hea-Young ; Estes, Cory R. ; Duncan, Andrew G. ; Wade, Brad D. ; Cleary, Florine C. ; Lloyd, Christopher R. ; Ellis, Walther R., Jr. ; Powers, Linda S.
Author_Institution :
Nat. Center for the Design of Molecular Function, Utah State Univ., Logan, UT, USA
Volume :
23
Issue :
1
fYear :
2004
Firstpage :
122
Lastpage :
129
Abstract :
We demonstrate the utility of this molecular engineering-based capture and detection technology for use in homeland defense. This capture technology can be placed on a "chip" where each section contains a different ligand. Intrinsic fluorescence is then used to monitor the binding of biomaterial in each section containing a ligand and determines the nature of the biomaterial (e.g., live bacterial cells, dead cells, spores, or tryptophan/tyrosine containing protein molecules).
Keywords :
biohazards; biosensors; fluorescence; molecular biophysics; proteins; terrorism; biomaterial; detection technology; fluorescence; homeland defense; microbial contamination; molecular engineering-based capture; protein molecules; real-time detection; Cardiac disease; Contamination; DNA; Fluorescence; Fungi; Laboratories; Microorganisms; Optical microscopy; Postal services; Production; Bacteria; Biosensing Techniques; Bioterrorism; Colony Count, Microbial; Environmental Microbiology; Environmental Monitoring; Equipment Design; Microbiological Techniques; Online Systems; Security Measures; Viruses;
fLanguage :
English
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
Publisher :
ieee
ISSN :
0739-5175
Type :
jour
DOI :
10.1109/MEMB.2004.1297183
Filename :
1297183
Link To Document :
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