اثر هشت هفته تمرين استقامت هوازي بر تغييرات نسفاتين -1 و گرلين آسيل دار در مردان چاق جوان

The effect of 8 weeks aerobic exercise on Nesfatin-1 and acylated Ghrelin in young obese men

نسفاتين-1 و گرلين دو پپتيد موثر در تنظيم تعادل انرژي هستند كه بررسي تغييرات آنها در اثر فعاليت بدني داراي اهميت است. هدف از پژوهش حاضر بررسي اثر هشت هفته تمرين هوازي بر نسفاتين-1 و گرلين آسيل دار پلاسمايي مردان چاق جوان است. روش كار: اين مطالعه نيمه تجربي در سال 1392 در شهر رشت انجام شد. در اين پژوهش، 21 داوطلب چاق (30

Introduction: Nesfatin-1 and ghrelin are two effective peptides in the regulation of energy balance. The purpose of this study was to examine the effect of eight weeks aerobic endurance training on nesfatin-1 and acylated ghrelin in obese men. Subjects and Methods: Twenthy one obese volunteer men randomly divided into the training and control groups. Training group was run with the intensity (55-65% max), 45 min, 4 days/week, for 8 weeks. Nesfatin-1, acylated ghrelin (ELISA), body composition and VO2 max of the subjects measured pre and post 8 weeks. Results: The results of independent t-Test showed that the 8 weeks aerobic endurance training did not have significant effect on serum nesfatin-1 and plasma acylated ghrelin levels. In training group, nesfatin-1 decreased and acylated ghrelin increased, but none of these variables showed significant changes like percentages of body fat and BMI. Conclusion: Thus, it seemed the levels of plasma acylated ghrelin and serum nesfatin-1, consequent of loosing weight by aerobic training, increased and decreased, respectively.