اﺛﺮ ﯾﮏ ﺟﻠﺴﻪ ورزش ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪت ﺑﺎﻻ ﺑﺮ ﻋﻮاﻣﻞ اﻧﻌﻘﺎدي و ﻓﯿﺒﺮﯾﻨﻮﻟﯿﺰ ﺧﻮن، ﻗﺒﻞ و ﺑﻌﺪ از 10 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ در ﮐﻮدﮐﺎن ﭼﺎق

The Effect of An Acute High Intensity Resistance Exercise on Blood Coagulation and Fibrinolysis Factors Pre-and Post 10 Weeks Resistance Training in Obese Children

ﻫﺪف از ﭘﮋوﻫﺶ ﺣﺎﺿﺮ، ﺑﺮرﺳﯽ اﺛﺮ ﯾﮏ ﺟﻠﺴﻪ ورزش ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪت ﺑﺎﻻ ﺑﺮ ﻋﻮاﻣﻞ اﻧﻌﻘﺎدي و ﻓﯿﺒﺮﯾﻨﻮﻟﯿﺰ، ﻗﺒﻞ و ﺑﻌﺪ از 10 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ در ﮐﻮدﮐﺎن ﭼﺎق ﺑﻮد. ﺑﺪﯾﻦﻣﻨﻈﻮر، 30 ﮐﻮدك ﭘﺴﺮ ﭼﺎق ﻫﺸﺖ ﺗﺎ 12 ﺳﺎل )ﺑﺎ ﺷﺎﺧﺺ ﺗﻮدة ﺑﺪن 27/08±0/96 ﮐﯿﻠﻮﮔﺮم ﺑﺮ ﻣﺘﺮ ﻣﺮﺑﻊ( ﺑﻪ دو ﮔﺮوه ﺗﻤﺮﯾﻦ و ﮐﻨﺘﺮل ﺗﻘﺴﯿﻢ ﺷﺪﻧﺪ. ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ ﺑﻪﺻﻮرت ﺳﻪ ﺟﻠﺴﻪ در ﻫﻔﺘﻪ و ﺑﻪﻣﺪت 10 ﻫﻔﺘﻪ ﺑﺎ ﺷﺪت 60ـ40 درﺻﺪ ﯾﮏ ﺗﮑﺮار ﺑﯿﺸﯿﻨﻪ ﺑﺮاي ﻫﺸﺖ ﺣﺮﮐﺖ اﺟﺮا ﺷﺪ. ورزش ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪت ﺑﺎﻻ ﺷﺎﻣﻞ دو ﺳﺖ 12 ﺗﮑﺮاري ﺑﺎ 75 درﺻﺪ ﯾﮏ ﺗﮑﺮار ﺑﯿﺸﯿﻨﻪ ﺑﺮاي ﻫﺸﺖ ﺣﺮﮐﺖ ﺑﻮد. ﺧﻮنﮔﯿﺮي در ﭼﻬﺎر ﻣﺮﺣﻠﻪ، ﻗﺒﻞ و ﺑﻌﺪ از دورة ﺗﻤﺮﯾﻨﯽ در دو ﻧﻮﺑﺖ )ﻗﺒﻞ و ﺑﻼﻓﺎﺻﻠﻪ ﭘﺲ از ﻓﻌﺎﻟﯿﺖ ﺣﺎد( اﻧﺠﺎم ﺷﺪ. ﺑﺮﻣﺒﻨﺎي ﻧﺘﺎﯾﺞ ﻣﺸﺎﻫﺪه ﻣﯽﺷﻮد ﮐﻪ ﯾﮏ ﺟﻠﺴﻪ ﻓﻌﺎﻟﯿﺖ ﻣﻘﺎوﻣﺘﯽ ﺑﺎ ﺷﺪت ﺑﺎﻻ ﺑﺎﻋﺚ اﻓﺰاﯾﺶ ﺳﻄﻮح ﻋﺎﻣﻞ ﻓﻌﺎلﮐﻨﻨﺪة ﭘﻼﺳﻤﯿﻨﻮژن ﺑﺎﻓﺘﯽ و وان وﯾﻠﺒﺮاﻧﺪ و ﮐﺎﻫﺶ ﻋﺎﻣﻞ ﻣﻬﺎرﮐﻨﻨﺪة ﻓﻌﺎلﮐﻨﻨﺪة ﭘﻼﺳﻤﯿﻨﻮژن ـ 1 ﺷﺪه اﺳﺖ؛ اﻣﺎ در ﻫﯿﭻﯾﮏ از ﮔﺮوهﻫﺎ ﺗﻐﯿﯿﺮي در ﺳﻄﻮح ﭘﺮوﺗﺌﯿﻦ S، ﭘﺮوﺗﺌﯿﻦ C، ﺗﻌﺪاد ﭘﻼﮐﺖﻫﺎ، زﻣﺎن ﻧﺴﺒﯽ ﺗﺮوﻣﺒﻮﭘﻼﺳﺘﯿﻦ و زﻣﺎن ﭘﺮوﺗﺮوﻣﺒﯿﻦ در ﭘﺎﺳﺦ ﺑﻪ ﯾﮏ ﺟﻠﺴﻪ ﻓﻌﺎﻟﯿﺖ ﻣﻘﺎوﻣﺘﯽ ﻣﺸﺎﻫﺪه ﻧﻤﯽﺷﻮد. ﺳﻄﻮح D ـ داﯾﻤﺮ ﻧﯿﺰ ﺗﻨﻬﺎ در ﮔﺮوه ﺗﻤﺮﯾﻦ در ﭘﺎﺳﺦ ﺑﻪ ﻓﻌﺎﻟﯿﺖ اﻓﺰاﯾﺶ ﯾﺎﻓﺘﻪ اﺳﺖ. ﻋﻼوهﺑﺮاﯾﻦ، ﺗﻔﺎوت ﺑﯿﻦﮔﺮوﻫﯽ در ﺳﻄﻮح ﻓﯿﺒﺮﯾﻨﻮژن و اﯾﻨﺘﺮﻟﻮﮐﯿﻦ6 ﻣﺸﺎﻫﺪه ﻣﯽﺷﻮد. ﻫﻤﭽﻨﯿﻦ، ﯾﺎﻓﺘﻪﻫﺎ ﺣﺎﮐﯽ از آن اﺳﺖ ﮐﻪ ﺗﻐﯿﯿﺮات ﻋﻮاﻣﻞ ﻓﯿﺒﺮﯾﻨﻮﻟﯿﺰ و اﻧﻌﻘﺎدي ﻗﺒﻞ از ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ در ﻫﺮ دو ﮔﺮوه ﮐﻨﺘﺮل و ﺗﻤﺮﯾﻦ در ﭘﺎﺳﺦ ﺑﻪ ورزش ﻣﻘﺎوﻣﺘﯽ ﺣﺎد ﺗﻘﺮﯾﺒﺎً ﻣﺸﺎﺑﻪ ﻣﯽﺑﺎﺷﺪ؛ اﻣﺎ ﭘﺲ از ﺳﺎزﮔﺎري ﺑﺎ ﺗﻤﺮﯾﻨﺎت ﻣﻘﺎوﻣﺘﯽ، در ﮔﺮوه ﺗﻤﺮﯾﻦ ﻣﻘﺎوﻣﺘﯽ اﻓﺰاﯾﺶ ﻋﻮاﻣﻞ ﻓﯿﺒﺮﯾﻨﻮﻟﯿﺰ و ﮐﺎﻫﺶ ﻋﻮاﻣﻞ اﻧﻌﻘﺎدي و اﻟﺘﻬﺎﺑﯽ در ﭘﺎﺳﺦ ﺑﻪ ﯾﮏ ﺟﻠﺴﻪ ورزش ﻣﻘﺎوﻣﺘﯽ ﺣﺎد ﻣﺸﺎﻫﺪه ﻣﯽﺷﻮد ﮐﻪ ﺑﺎ ﺳﻄﻮح ﭘﻼﺳﻤﺎﯾﯽ ﻋﺎﻣﻞ ﻓﻌﺎلﮐﻨﻨﺪة ﭘﻼﺳﻤﯿﻨﻮژن ﺑﺎﻓﺘﯽ ، Dـ داﯾﻤﺮ و ﻋﺎﻣﻞ وانوﯾﻠﺒﺮاﻧﺪ ﺑﺎﻻﺗﺮ و ﺳﻄﻮح اﯾﻨﺘﺮﻟﻮﮐﯿﻦ6، ﻋﺎﻣﻞ ﻣﻬﺎرﮐﻨﻨﺪة ﻓﻌﺎلﮐﻨﻨﺪة ﭘﻼﺳﻤﯿﻨﻮژن ـ 1 و ﻓﯿﺒﺮﯾﻨﻮژن ﭘﺎﯾﯿﻦﺗﺮ ﻧﺸﺎن داده ﺷﺪه اﺳﺖ.

The aim of this study was to evaluate the effect of an acute high intensity resistance exercise (AHIRE) on blood coagulation and fibrinolysis factors pre-and post 10 weeks resistance training in obese children. 30 obese children (8-12 yr) voluntary with body mass index 27.08±0.96 kg/m2 were divided into control and training groups. The resistance training consists of ten weeks (3 times per week) with the intensity of 40-60% 1 repetition maximum (1RM) for eight exercises. Acute high intensity resistance exercise includes 2 sets of 12 repetitions with 75%1-RM for eight exercises. Blood samples were taken 4 times before and after training period (before and immediately after acute exercise). The AHIRE causes increase in tPA and vWF and causes decrease in PAI-1. There were no signigicant changes in protein S, protein C levels, platelet count, aPPT and PT in response to AHIRE in control and training groups. D-dimer levels increased in respose to exercise in taining group only. Also, ten weeks resistnace training causes reduction in fibrinogen and IL-6 levels in response to AHIRE compared to the control group. Before resistance training the results suggested that changes in coagulation and fibrinolysis factors were similar in both control and training groups approximately, in response to AHIRE. But after adaptation to resistance training, the training group showed higher fibrinolysis factors and lower coagulation and inflammation factors in response to AHIRE, that was showed with elevation in tPA, D-dimer and vWF and reduction in IL-6 and fibrinogen levels.