تاثير تمرين مقاومتي كوتاه مدت با دو شدت متفاوت بر غلظت سرمي سيتوكين هاي ضدالتهابي و مقادير تري گليسيريد و گليكوژن كبدي موش هاي صحرايي

Effects of short term resistance training with different intensity on serum levels of anti-inflammatory cytokines and liver triglycerides and glycogen contents in rats

مقدمه و هدف: امنتين-1 آديپوكين تازه شناخته شده‌ اي با ويژگي‌ هاي ضدالتهابي و افزايش حساسيت انسوليني است كه نقش مهمي در پاتوژنز چاقي و بيماري‌ هاي مرتبط با آن دارد. هدف اين پژوهش، بررسي تاثير تمرين مقاومتي با شدت‌ هاي مختلف بر سطوح سرمي امنتين-1 و آديپونكتين همراه با مقادير تري‌ گليسيريد و گليكوژن كبدي موش‌ هاي صحرايي نر بالغ بود. روش‌ شناسي: 24 سر موش صحرايي نر از نژاد ويستار (12 تا 14 هفته‌ اي) به طور تصادفي به 3 گروه كنترل، تمرين مقاومتي با بار معادل 50% وزن بدن (تمرين 1) و تمرين مقاومتي با بار معادل 100% وزن بدن (تمرين 2) تقسيم شدند. تمرين مقاومتي شامل بالا رفتن از نردبان با وزنه‌هاي متصل به دم حيوانات بود. به منظور تعيين غلظت سرمي امنتين-1 و آديپونكتين از روش الايزا استفاده شد. يافته‌ ها: پس از 4 هفته تمرين مقاومتي تفاوت معني‌ داري در غلظت سرمي امنتين-1، آديپونكتين و گلوكز گروه‌هاي مختلف مشاهده نشد (0/05

Introduction and purpose: Omentin-1 is a novel adipokine with insulin sensitizing and anti-inflammatory properties that plays a key role in the pathogenesis of obesity and concomitant diseases. The purpose of this study was to investigate the effects of resistance training with different intensity on serum levels of omentin-1 and adiponectin as well as liver triglycerides and glycogen contents in adult male rats. Materials and methods: Twenty four male Wister rats (12-14 Weeks old) were randomly divided into three groups: control, resistance training with 50% body mass (training 1), and resistance training with 100% body mass (training 2). The resistance training consisted of climbing a ladder carrying a load suspended from the tail. ELISA method was used to determine serum omentin-1 and adiponectin concentrations. Results: After four weeks of resistance training we did not find any significant differences in serum omentin-1, adiponectin and glucose concentrations between all groups. The amount of liver triglycerides in training 1 and 2 groups were lower compared with control group (respectively, P= 0.01 & P= 0.009). Liver glycogen content in training 2 group was significantly higher compared with the control group (P= 0.01). Discussion and conclusion: These results indicated that short-term resistance training could change liver triglycerides and glycogen contents without significant changes in serum omentin-1 and adiponectin levels in rats.