تأثير 8 هفته تمرين استقامتي بر سطح سرمي اينترلوكين 10 و تركيب بدني زنان غيرفعال داراي اضافه وزن

The effects of 8 weeks of endurance exercise training on IL-10 level and body composition of sedentary overweight women

زمينه و هدف: بر اساس شواهد موجود، فعاليت ورزشي منظم مي­تواند موجب كاهش التهاب مزمن شود. هدف از تحقيق حاضر بررسي تأثير 8 هفته تمرين استقامتي بر سطح سرمي اينترلوكين 10 و تركيب بدني زنان غيرفعال داراي اضافه وزن بود. روش تحقيق: 22 زن غيرفعال از زنان ميانسال شهر پرديس داراي اضافه وزن (25p استفاده شد. يافته ها: درصد چربي (002/0=p)، شاخص توده بدني (01/0=p) و نسبت دور كمر به دور لگن (04/0=p) گروه تجربي نسبت به گروه كنترل كاهش معني داري نشان داد، در حالي­كه توده بدون چربي (11/0=p) و سطح سرمي اينترلوكين 10 (52/0=p) تغيير معني دار نكرد. نتيجه گيري: فعاليت ورزشي استقامتي از طريق بهبود تركيب بدني مي­تواند نقش مهمي در پيشگيري از ابتلا به بيماري هاي مرتبط با اضافه وزن و چاقي داشته باشد؛ اما براي براي دست يابي به اثرات ضد التهابي اين نوع فعاليت ورزشي، احتمالا به مطالعات بيشتري نياز است.

Background and Aim: According recent evidence, regular exercise training can reduce the chronic inflammation. The aim of this study was to investigate the effect of 8 weeks of endurance exercise training on serum levels of IL-10 and body composition of sedentary overweight women. Materials and Methods: Twenty tow middle aged overweight (BMI>25 kg/m2) and sedentary women were from Pardis city randomized divided into two groups including control (C) and exercise training (EX) groups. Endurance exercise training group participated in running exercise on a treadmill (three sessions per week) for 8 weeks, 20-30 min per session, at 50-70% their maximal reserve heart rate. Blood samples were collected in fasting state at 48 hours before starting training and 48 hours after last exercise session. IL-10 level were measured ELISA assay. Results were extracted by analysis of covariance (ANCOVA) method at significant level of pResults: Body fat percent (p=0.002), BMI (p=0.01 ) and WHR (p=0.04) of exercise group significantly decreased in compare to control group but there was no significant changes in IL-10 (p=0.52) levels and fat-free mass (p=0.11). Conclusion: Endurance exercise training can play important role in prevention of diseases-induced overweight by improvement of body composition; however it seems that more studies will be needed for obtaining the anti-inflammatory effects of such exercise.